ONO-2020-02 — Alzheimer’s Disease
The ONO-2020-02 Study is looking at an investigational drug for people with mild to moderate Alzheimer’s disease. The investigational drug is aimed at helping people who are living with Alzheimer’s disease with their symptoms. Specifically, the study is looking to see:
- how safe the investigational drug is
- what side effects it causes
- how well the body processes it
- if it might help to improve Alzheimer’s symptoms, such as memory loss
The study will last for up to 9 months. There will be 10 study center visits.
ADAGIO-1 — Agitation in adults with Alzheimer’s Disease
If you or someone you know is experiencing agitation related to Alzheimer’s disease, the ADAGIO-1 Study (CN012-0023) may interest you. Agitation is one of the most common features of Alzheimer’s disease, and it can cause a person to become restless, irritable, upset, or even aggressive. Agitation can significantly impact quality of life for both the person with the condition and their caregivers.
The ADAGIO-1 Study is testing an oral study drug to see if it can safely treat agitation.
The study is seeking 352 participants form about 100 clinic sites around the world.
CATALPA — Cervical Dystonia
This is study is currently open for enrollment and is testing whether an investigational drug can reduce pain, improve quality of life, and delay the return of symptoms for people with cervical dystonia. Safety and efficacy (how well something works) will also be tested.
The investigational drug is called IPN10200. It is based on botulinum toxins that doctors can give to people with cervical dystonia. IPN10200 may have a longer-lasting effect than currently used natural versions. This may mean fewer injections are needed. The CATALPA Study will compare IPN102000 with placebo. The stud placebo looks exactly like IPN10200 but does not contain any medically active ingredients.
You will have a 2 in 3 chance of receiving IPN10200, and a 1 in 3 chance of receiving placebo. This will be picked randomly. At one study visit only, the study doctor will inject IPN10200 or placebo into muscles around your head, neck, and shoulder.